The Drug Targets siRNA library consists of high-confidence gene targets based on publications that characterize potential druggable targets and was assembled with use of innovative bioinfomatics tools to analyze genetic and ontological information from multiple databases. This siRNA collection excludes gene targets available in other siRNA libraries: kinases, g-protein coupled receptors, proteases, phosphatases, ion channels, and genes involved with ubiquitin conjugation.
Internal validation and peer-reviewed publications report numerous successes with difficult-to-transfect cell types. See the References tab for a list of publications.
(1) Combine Accell siRNA with Accell delivery media (or other low- or no-serum media). (2) Add Accell delivery mix directly to cells, and incubate for 72 hours.