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Choose from our predesigned products lines of lentiviral sgRNA, shRNA, and
over-expression reagents to build your own custom library.
When Dharmacon pre-defined sgRNA, shRNA, or over-expression libraries do not match your experimental requirements, you can make your own custom clone library with ease, speed and economy.
You can cherry-pick from our glycerol stock format sgRNA, shRNA, and mammalian over-expression product lines for human and mouse reagents to create the ideal clone collection for your particular needs.
Which shRNA product is right for you?
Dharmacon offers three complete predesigned product lines across human and mouse genomes. Use the table below to help you in determining the right shRNA product for your needs.
Which over-expression product is right for you?
Dharmacon offers five different mammalian open reading frame (ORF) collections and the Mammalian Genome Collection (MGC) cDNA collection. Use the table below to help you in determining the right over-expression product for your needs.
All products are delivered as arrayed glycerol stocks in 96-well plates
Select from our predesigned Edit-R Lentiviral sgRNA Druggable Genome collection with up to 4 sgRNA constructs per gene; minimum 20 constructs per order. We recommend choosing 3-4 constructs per gene.
Select from either: GIPZ, TRIPZ, or TRC lentiviral shRNA collections; minimum 20 constructs per order. We recommend selecting 3-5 constructs per gene.
MGC collection: Cannot be mixed with other collections, minimum 20 constructs per order; clones will be plated according to antibiotic requirements
May be combined with other ORF collections to increase coverage for desired library; minimum 20 constructs from a single collection per order. Clones will be plated by collection. (e.g. a customer library of 20 ORFeome collaboration clones and 5 hORFeome v8.1 clones will qualify for library plating, a custom library of 15 ORFeome collaboration clones and 10 hORFeome v8.1 will not)
Investigation of entire gene families or biological pathways is enabled by our broad suite of custom and pre-defined libraries of
CRISPR-Cas9 reagents that take advantage of our algorithm-optimized
guide RNA designs for high functionality and superior specificity.
High-titer pooled screening libraries for pre-defined gene sets in human and mouse.
Arrayed collections of lentiviral sgRNA libraries for high-throughput knockout screening across entire human gene families.
Designed using microRNA scaffold-specific attributes for highly efficient processing via the endogenous RNAi pathway while minimizing off-target potential
Advanced rationally-designed microRNA-based shRNA for human, mouse, and rat genes. Choose from seven constitutive promoters and three reporter options to tailor SMARTvector shRNA for specific cells.
All the benefits of SMARTvector lentiviral shRNAs combined with latest generation of powerful Tet-inducible technology for unprecedented control over gene silencing and reduced off-targeting.
Efficient gene silencing with a microRNA-adapted shRNA design. Available as lentiviral vector constructs or high-titer lentiviral particles for human and mouse
Inducible shRNA expression allows for tightly regulatable RNAi experiments. Available as lentiviral vector constructs for human.
High-titer pooled screening libraries of constitutive shRNAs for pre-defined gene libraries in human, mouse, and rat
High-titer pooled screening libraries of inducible shRNAs for pre-defined gene libraries in human, mouse, and rat.
High-titer pooled screening libraries of constitutive shRNAs for pre-defined gene libraries in human.
Offers a classic hairpin, rules-based shRNA design utilizing a simple hairpin of 21 base pair sense and antisense stem, and a 6 basepair loop
Lentiviral shRNA collection from The RNAi Consortium (TRC) with coverage in human and mouse.
Pre-defined gene family collections are available for many of our cDNA and ORF products. Choose the product line that best fits your experimental needs.
The mouse and human MGC libraries contain popular gene families in expression-ready and other vector backbones.
Expression-ready open reading frames (ORFs) that have been cloned into a lentiviral expression vector with a GFP reporter.
Expression-ready human ORFs in a lentiviral vector, stop codons have been removed and clones contain a C-terminal V5 tag.
Sequence-verified human and mouse open reading frames (ORFs) subcloned into Gateway® recombinational entry vectors.
Fully-sequenced collection of Gateway-adapted ORFs representing the latest version of the CCSB Human ORFeome library from Dana-Farber Cancer Institute.
The Gateway® adapted human Entry ORF libraries, ideal for easily moving entire families of ORFs into your choice of protein expression systems.