The Dharmacon Horizon Discovery will be undergoing maintenance on Monday November 19th. The website may be intermittently unavailable from 12:00 p.m. to 6:00 p.m. (MST). We appreciate your patience during this time period. If you need assistance please reach out to our
customer support team.
Home | Resources | FAQs
What is the purpose of the Central Polypurine tract (cPPT) on your viral vectors?
The Central Polypurine tract helps with transduction into non-dividing cells. Although no one really understands the mechanism by which the Central Polypurine tract helps translocation into the nucleus of nondividing cells at this time, it appears to allow the virus to penetrate the nuclear membrane.
Some links to literature: