How much siRNA should I order for an in vivo mouse study?

As in vivo work with siRNA is relatively new, there are few established procedures and thus it is difficult to say exactly how much siRNA would be needed for these experiments. We recommend that a literature search be performed to identify other in vivo studies that use a similar route of administration and target tissue. We encourage investigators to consult PubMed or HighWire for similar studies to determine specific delivery needs.