How do miRIDIAN microRNA Hairpin Inhibitors differ from 2'-O-methyl oligos?

The miRIDIAN microRNA Hairpin Inhibitors are single-stranded chemically-modified RNA oligonucleotides designed to inhibit the function of endogenous miRNA. miRIDIAN microRNA Hairpin Inhibitors specifically target each mature microRNA as derived from a unique precursor and exhibit greater potency and longevity than 2' –O- methyl RNA oligos that are antisense to the mature microRNA. For additional information please read the miRIDIAN brochure and flier.