IQGAP1( Human )

Entrez Gene 8826 Entrez Gene 8826
IQ motif containing GTPase activating protein 1

Alias

HUMORFA01|SAR1|p195

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008].

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