PEA15( Human )

Entrez Gene 8682 Entrez Gene 8682
phosphoprotein enriched in astrocytes 15

Alias

HMAT1|HUMMAT1H|MAT1|MAT1H|PEA-15|PED

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].

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