ABRAXAS1( Human )

Entrez Gene 84142 Entrez Gene 84142
abraxas 1, BRCA1 A complex subunit

Alias

ABRA1|CCDC98|FAM175A

This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].

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