ARHGAP24( Human )
Rho GTPase activating protein 24
Alias
FILGAP|RC-GAP72|RCGAP72|p73|p73RhoGAP
This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].