LAGE3( Human )

Entrez Gene 8270 Entrez Gene 8270
L antigen family member 3

Alias

CVG5|DXS9879E|DXS9951E|ESO3|ITBA2|Pcc1

This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008].

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