THOP1( Human )

Entrez Gene 7064 Entrez Gene 7064
thimet oligopeptidase 1

Alias

EP24.15|MEPD_HUMAN|MP78|TOP

The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015].

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