BCL2( Human )

Entrez Gene 596 Entrez Gene 596
BCL2, apoptosis regulator

Alias

Bcl-2|PPP1R50

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

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