MBL2( Human )
mannose binding lectin 2
Alias
COLEC1|HSMBPC|MBL|MBL2D|MBP|MBP-C|MBP1|MBPD
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008].