M6PR( Human )

Entrez Gene 4074 Entrez Gene 4074
mannose-6-phosphate receptor, cation dependent

Alias

CD-M6PR|CD-MPR|MPR 46|MPR-46|MPR46|SMPR

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011].

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