PABPC1( Human )

Entrez Gene 26986 Entrez Gene 26986
poly(A) binding protein cytoplasmic 1

Alias

PAB1|PABP|PABP1|PABPC2|PABPL1

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010].

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