CELSR3( Human )

Entrez Gene 1951 Entrez Gene 1951
cadherin EGF LAG seven-pass G-type receptor 3

Alias

ADGRC3|CDHF11|EGFL1|FMI1|HFMI1|MEGF2|RESDA1

This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013].

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