DDOST( Human )

Entrez Gene 1650 Entrez Gene 1650
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

Alias

AGER1|CDG1R|GATD6|OKSWcl45|OST|OST48|WBP1

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008].

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