MERTK( Human )

Entrez Gene 10461 Entrez Gene 10461
MER proto-oncogene, tyrosine kinase

Alias

MER|RP38|Tyro12|c-Eyk|c-mer

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008].

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