CD2BP2( Human )

Entrez Gene 10421 Entrez Gene 10421
CD2 cytoplasmic tail binding protein 2

Alias

FWP010|LIN1|PPP1R59|Snu40|U5-52K

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008].

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