DharmaFECT Transfection Reagents

siRNA and microRNA Transfection

To attain efficient and reliable siRNA or microRNA transfection, we offer DharmaFECT 1-4 transfection reagents.

• Optimized for small RNA (siRNA or microRNA) delivery, DharmaFECT provides four specialized lipid-based formulations for successful delivery to more cell lines than any other single reagent.


• DharmaFECT 1 is the most all-purpose transfection reagent, demonstrating efficient, low-toxicity delivery to over 80% of validated cell types.


• DharmaFECT 2, 3, and 4 offer distinct formulations to support a wider range of cell types, and permit more thorough optimization of transfection for high-value experiments and screening projects.


• Use the DharmaFECT Cell Type Guide to review validated formulations for common cell types.

Plasmid Transfection

• DharmaFECT kb is optimized to deliver plasmid DNA at low concentrations with minimal amount of transfection reagent and high cell viability.

Co-transfection of small RNA and plasmid DNA

• DharmaFECT Duo is the only optimized reagent to deliver both small RNA reagents with plasmid DNA.

siRNA and microRNA Transfection

Optimized for small RNA (siRNA or microRNA) delivery

• DharmaFECT 1 Transfection Reagent

  The most broadly applicable DharmaFECT formulation for optimal siRNA or microRNA transfection into a wide range of cell types for successful RNAi experiments. DharmaFECT 1 has been validated in over 35 cell types.

• DharmaFECT 2 Transfection Reagent

  One of four siRNA/microRNA specific formulations, DharmaFECT 2 is a chemically distinct alternative to one-size-fits-all transfection reagents to achieve high-efficiency silencing in more cell types.

• DharmaFECT 3 Transfection Reagent

  One of four siRNA/microRNA specific formulations, DharmaFECT 3 is a chemically distinct alternative to one-size-fits-all transfection reagents to achieve high-efficiency silencing in more cell types.

• DharmaFECT 4 Transfection Reagent

  DharmaFECT 4 Transfection Reagent is chemically distinct from the other DharmaFECT formulations, providing an alternative when DharmaFECT 1 does not achieve optimal results, and is ideal to include in transfection optimization experiments prior to RNAi screening or other high-value experiments

• DharmaFECT Set of 4 Transfection Reagents

  An aliquot of each of the four DharmaFECT formulations for siRNA/microRNA transfection optimization studies. Useful for determination of the best reagent for your cells and particular experimental conditions.

• DharmaFECT Duo Transfection Reagent

  Optimized for co-transfection, DharmaFECT Duo transfection reagent provides highly effective delivery of siRNA, microRNA or crRNA reagents with plasmid.

• DharmaFECT kb DNA Transfection Reagent

  Efficient transfection of plasmid DNA.

DharmaFECT Resources