FGFBP1( Human )

Entrez Gene 9982 Entrez Gene 9982
fibroblast growth factor binding protein 1

Alias

FGF-BP|FGF-BP1|FGFBP|FGFBP-1|HBP17

This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011].

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