SETDB1( Human )
SET domain bifurcated 1
Alias
ESET|H3-K9-HMTase4|KG1T|KMT1E|TDRD21
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011].