AATK( Human )

Entrez Gene 9625 Entrez Gene 9625
apoptosis associated tyrosine kinase

Alias

AATYK|AATYK1|LMR1|LMTK1|PPP1R77|p35BP

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].

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