PRPF4( Human )
pre-mRNA processing factor 4
Alias
HPRP4|HPRP4P|PRP4|Prp4p|RP70|SNRNP60
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016].