DIRAS3( Human )

Entrez Gene 9077 Entrez Gene 9077
DIRAS family GTPase 3

Alias

ARHI|NOEY2

This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015].

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