Search
Contact Us
Cart
Toggle Mobile Navigation
Products
Pin-point™ Base Editing Platform
All Dharmacon™ Reagents
Gene Editing
Gene Editing
show/hide subitems
Explore Gene Editing
CRISPR guide RNA
Cas9 nucleases
Controls
Custom guide RNA
Knock-in templates
Cherry-pick library tool - clones
Cherry-pick library tool - synthetic
CRISPR libraries
Gene Knockdown
Gene Knockdown
show/hide subitems
Explore Gene Knockdown
siRNA
shRNA
microRNA
Controls
lncRNA
Custom siRNA design
Cherry-pick library tool - synthetic
Cherry-pick library tool - clones
RNAi libraries
Gene Expression
Gene Expression
show/hide subitems
Explore Gene Expression
CRISPRa
cDNA & ORFs
CRISPR Modulation
CRISPR Modulation
show/hide subitems
Explore CRISPR Modulation
CRISPRi
CRISPRa
CRISPRa libraries
dCas9 stable cell lines
Controls
Reference Standards
Reference Standards
show/hide subitems
Explore Reference Standards
Create your own reference standard
Oncospan
Analysis technique
Sample type
Format
Libraries
Libraries
show/hide subitems
Explore Libraries
CRISPR libraries
RNAi libraries
Cherry-pick library tool - clones
Cherry-pick library tool - synthetic
Engineered Cell Models
Engineered Cell Models
show/hide subitems
Explore Engineered Cell Models
Knockout cell lines
Double knockout cell lines
Cancer related cell lines
Cas9 stable cell lines
dCas9 stable cell lines
Custom Oligonucleotides
Custom Oligonucleotides
show/hide subitems
Explore Custom Oligonucleotides
Single-strand RNA synthesis
Custom siRNA
Custom antisense oligonucleotides
Custom DNA
Custom microRNA
Non-mammalian research
Transfection & Ancillary Reagents
Bioproduction Cell Lines
Bioproduction Cell Lines
show/hide subitems
Explore Bioproduction Cell Lines
CHOSOURCE™ expression platform
CHOSOURCE™ ADCC+ cell line
CHOSOURCE™ TnT transposon technology
Services
Functional Genomic Screening
Functional Genomic Screening
show/hide subitems
Explore Functional Genomic Screening
Arrayed screens
Pooled screens
CRISPR screens
RNAi screens
Single-cell CRISPR screens
Immune cell screens
Pin-point base editing
Immune Cell Screening
Immune Cell Screening
show/hide subitems
Explore Immune Cell Screening
CRISPR immune cell screens
Custom immune cell screens
Compound screening assays
iTreg Polarization assay
iTreg Suppression assay
T Cell Activation assay
Mixed Lymphocyte Reaction assay
Cell Panel Screening
Cell Panel Screening
show/hide subitems
Explore Cell Panel Screening
2D OncoSignature
2D OncoSignature Long-term assay
3D OncoSignature
Custom screens
Cell Line Engineering
Cell Line Engineering
show/hide subitems
Explore Cell Line Engineering
Knockout
Knock-in
Bioproduction cell engineering
Custom Libraries
Custom Oligonucleotides
Contract Research Services
Pin-point™ Base Editing Services
Custom Reference Standards
Application Areas
Gene Editing
Gene Editing
show/hide subitems
Explore Gene Editing
Engineering a knockout cell line
Synthetic sgRNA for CRISPR-Cas9 experiments
CRISPR-Cas9 guide RNA algorithm
Inducible lentiviral Cas9 nuclease
Homology-directed repair with a DNA donor oligo
Homology-directed repair with a plasmid donor
Multiplex CRISPR-Cas9 knockout
All-in-one CRISPR knockout
Synthetic lethality
CRISPRmod
CRISPRmod
show/hide subitems
Explore CRISPRmod
CRISPR interference
CRISPR activation
CRISPRa MS2 tracrRNA
All-in-one CRISPR modulation
RNA Interference
RNA Interference
show/hide subitems
Explore RNA Interference
siRNA
Self-delivering siRNA
shRNA
microRNA
Noncoding RNA
Engineered Cell Lines
Engineered Cell Lines
show/hide subitems
Explore Engineered Cell Lines
Antibody validation
Autophagy pathway
Bromodomain containing proteins
Caspases
Deubiquinating enzymes (DUBs)
DNA damage pathways
Drug targets
Epigenetics
Histone acetylation
iPSCs
Kinase inhibition
mTOR pathway
Parkinson's disease
Phosphoinositide function
Phospholipases
Primary and stem cells
Rab GTPases
Serine threonine phosphatase
Sialylation pathway
Solute carrier slc gene
Sumoylation
TNF alpha
Ubiquitin conjugating enzymes
Functional Genomic Screening
Functional Genomic Screening
show/hide subitems
Explore Functional Genomic Screening
Screening validation and follow-up using engineered cell lines
Reverse transfection for high-throughput CRISPR studies
C911 controls for siRNA screening
Seed sibling controls for RNAi hit validation
cDNA/ORF Overexpression
Custom RNA synthesis
Custom RNA synthesis
show/hide subitems
Explore Custom RNA synthesis
Antisense oligos
Transfection
View all applications
Knowledge Base
Document Library
Document Library
show/hide subitems
Technical resources
Application notes
Exome data
Technical manuals
Protocols
Certificate of analysis
Posters
Publications
Quick protocols
Reading lists
Safety data sheets
Product data
White papers
Supporting resources
Brochures
eBooks
Selection guides
Product inserts
Education & Events
Education & Events
show/hide subitems
Explore Education & Events
Webinars
Events
Videos
Featured articles
On the Horizon Blog
On the Horizon Blog
show/hide subitems
Explore On the Horizon Blog
Gene editing
Gene modulation
Cell models
Screening
Reference standards
CRISPR modulation
Custom synthesis
Tech Tips
Tools & Calculators
Tools & Calculators
show/hide subitems
Explore Tools & Calculators
Biochemical conversion tools
OD conversion
DNA copy number calculator
Reagent calculator
siRNA/miRNA calculator for screening
DharmaFECT calculator for screening
BioIT beta tools
P-value to Z-score converter
T7EI calculator
nmol to µg calculator
Primer design & Analysis tools
Multiple primer analyzer
TM calculator
qPCR
qpcr efficiency calculator
FAQs
Vector maps & sequences
Support
How can we help you?
How can we help you?
show/hide subitems
Explore How can we help you?
Customer & scientific support
Products & Services FAQs
Products & Services FAQs
show/hide subitems
Explore Products & Services FAQs
Gene editing
Screening
Cell lines
Reference standards
Custom Synthesis
Transfection & transduction
Viral packaging
Ordering & Shipping
Ordering & Shipping
show/hide subitems
Explore Ordering & Shipping
Shipping & delivery dates
Account
Account
show/hide subitems
Explore Account
Reset password
Order history
Custom Ordering Tools
Custom Ordering Tools
show/hide subitems
Explore Custom Ordering Tools
CRISPR design tool
HDR donor design
Custom siRNA
siDESIGN center
Cherry-pick libraries
Custom microRNA
Custom SMARTpool
ssRNA synthesis
Custom DNA
Order Center
Ordering
Ordering
show/hide subitems
Quick Cart
Ordering information & forms
Legal entity for ordering
Learn how to create a quote
Helpful links
Helpful links
show/hide subitems
Request an invoice
eProcurement solutions
Shipping information
Need help?
Need help?
show/hide subitems
Customer & scientific support
About Us
Discover
Discover
show/hide subitems
Our company
Careers
Business model
Markets
Strategy
Learn
Learn
show/hide subitems
Blog
Events
News
Quality
eProcurement
Need help?
Need help?
show/hide subitems
Customer & scientific support
Select Language
Languages
Languages
show/hide subitems
English
Japanese
Afghanistan
Aland Islands
Albania
Algeria
American Samoa
Andorra
Angola
Anguilla
Antarctica
Antigua And Barbuda
Argentina
Armenia
Aruba
Australia
Austria
Azerbaijan
Bahamas
Bahrain
Bangladesh
Barbados
Belarus
Belgium
Belize
Benin
Bermuda
Bhutan
Bolivia, Plurinational State Of
Bonaire, Saint Eustatius And Saba
Bosnia
Botswana
Bouvet Island
Brazil
British Indian Ocean Territory
Brunei Darussalam
Bulgaria
Burkina Faso
Burundi
Cambodia
Cameroon
Canada
Cape Verde Islands
Cayman Islands
Central African Republic
Chad
Chile
China
Christmas Island
Cocos (Keeling) Islands
Colombia
Comoros
Congo
Congo, The Democratic Republic Of The
Cook Islands
Costa Rica
Côte d'ivoire (Ivory Coast)
Croatia
Curaçao
Cyprus
Czech Republic
Denmark
Djibouti
Dominica
Dominican Republic
Ecuador
Egypt
El Salvador
Equatorial Guinea
Eritrea
Estonia
Ethiopia
Falkland Islands (Malvinas)
Faroe Islands
Fiji
Finland
France
French Guiana
French Polynesia
French Southern Territories
Gabon
Gambia
Georgia
Germany
Ghana
Gibraltar
Greece
Greenland
Grenada
Guadeloupe
Guam
Guatemala
Guernsey
Guinea
Guinea-Bissau
Guyana
Haiti
Heard Island And Mcdonald Islands
Holy See (Vatican City State)
Honduras
Hong Kong
Hungary
Iceland
India
Indonesia
Iraq
Ireland
Isle Of Man
Israel
Italy
Jamaica
Japan
Jersey
Jordan
Kazakhstan
Kenya
Kiribati
Kosovo
Kuwait
Kyrgyzstan
Lao People's Democratic Republic
Latvia
Lebanon
Lesotho
Liberia
Libyan Arab Jamahiriya
Liechtenstein
Lithuania
Luxembourg
Macau
Macedonia
Madagascar
Malawi
Malaysia
Maldives
Mali
Malta
Marshall Islands
Martinique
Mauritania
Mauritius
Mayotte
Mexico
Micronesia, Federated States of
Moldova
Monaco
Mongolia
Montenegro
Montserrat
Morocco
Mozambique
Myanmar
Namibia
Nauru
Nepal
Netherlands
New Caledonia
New Zealand
Nicaragua
Niger
Nigeria
Niue
Norfolk Island
Northern Mariana Islands
Norway
Oman
Pakistan
Palau
Palestinian Territory, Occupied
Panama
Papua New Guinea
Paraguay
Peru
Philippines
Pitcairn
Poland
Portugal
Puerto Rico
Qatar
Réunion
Romania
Russian Federation
Rwanda
Saint Barthélemy
Saint Helena, Ascension And Tristan Da Cunha
Saint Kitts And Nevis
Saint Lucia
Saint Martin (French Part)
Saint Pierre And Miquelon
Saint Vincent And The Grenadines
Samoa
San Marino
Sao Tome And Principe
Saudi Arabia
Senegal
Serbia
Seychelles
Sierra Leone
Singapore
Sint Maarten (Dutch Part)
Slovakia
Slovenia
Solomon Islands
Somalia
South Africa
South Georgia And The South Sandwich Islands
South Korea
Spain
Sri Lanka
Suriname
Svalbard And Jan Mayen
Swaziland
Sweden
Switzerland
Taiwan
Tajikistan
Tanzania, United Republic Of
Thailand
Timor-Leste
Togo
Tokelau
Tonga
Trinidad And Tobago
Tunisia
Turkey
Turkmenistan
Turks And Caicos Islands
Tuvalu
Uganda
Ukraine
United Arab Emirates
United Kingdom
United States
United States Minor Outlying Islands
Uruguay
Uzbekistan
Vanuatu
Venezuela
Vietnam
Virgin Islands, British
Virgin Islands, U.S.
Wallis And Futuna
Western Sahara
Yemen
Yugoslavia
Zambia
Zimbabwe
Gene Landing Page
SGPL1
( Human )
Entrez Gene
8879
Entrez Gene 8879
sphingosine-1-phosphate lyase 1
Alias
S1PL|SPL
Product Category
siRNA
shRNA
CRISPR Guide RNA
Cell Line Models
cDNA / ORF
Filter
