MED25( Human )
mediator complex subunit 25
Alias
ACID1|ARC92|BVSYS|CMT2B2|P78|PTOV2|TCBAP0758
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010].