TERF1( Human )

Entrez Gene 7013 Entrez Gene 7013
telomeric repeat binding factor 1

Alias

PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008].

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