SRC( Human )

Entrez Gene 6714 Entrez Gene 6714
SRC proto-oncogene, non-receptor tyrosine kinase

Alias

ASV|SRC1|THC6|c-SRC|p60-Src

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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