RAC2( Human )

Entrez Gene 5880 Entrez Gene 5880
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

Alias

EN-7|HSPC022|p21-Rac2

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013].

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