PYCR1( Human )
pyrroline-5-carboxylate reductase 1
Alias
ARCL2B|ARCL3B|P5C|P5CR|PIG45|PP222|PRO3|PYCR
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].