DGCR8( Human )

Entrez Gene 54487 Entrez Gene 54487
DGCR8, microprocessor complex subunit

Alias

C22orf12|DGCRK6|Gy1|pasha

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].

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