MLXIPL( Human )

Entrez Gene 51085 Entrez Gene 51085
MLX interacting protein like

Alias

CHREBP|MIO|MLX|MONDOB|WBSCR14|WS-bHLH|bHLHd14

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].

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