MARCKS( Human )

Entrez Gene 4082 Entrez Gene 4082
myristoylated alanine rich protein kinase C substrate

Alias

80K-L|MACS|PKCSL|PRKCSL

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008].

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