HSD17B3( Human )
hydroxysteroid 17-beta dehydrogenase 3
Alias
EDH17B3|SDR12C2
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008].