BIRC2( Human )

Entrez Gene 329 Entrez Gene 329
baculoviral IAP repeat containing 2

Alias

API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

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