NR4A1( Human )
nuclear receptor subfamily 4 group A member 1
Alias
GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].