AES( Human )

Entrez Gene 166 Entrez Gene 166
amino-terminal enhancer of split

Alias

AES-1|AES-2|ESP1|GRG|GRG5|Grg-5|TLE5

The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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