AGAP2( Human )

Entrez Gene 116986 Entrez Gene 116986
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Alias

CENTG1|GGAP2|PIKE

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

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