ZMPSTE24( Human )
zinc metallopeptidase STE24
Alias
FACE-1|FACE1|HGPS|PRO1|STE24|Ste24p
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008].