Unleash the power of arrayed CRISPR screening!
The first arrayed synthetic crRNA library targeting over 18,000 human genes for CRISPR-Cas9 knockout screens is here!
Synthetic and lentiviral reagents for endogenous gene overexpression
Straightforward, efficient tools to perform gain-of-function studies on a few genes, or the whole human genome! Our predesigned reagents for human and mouse genes make it easy!
Guaranteed silencing in 3 easy steps
Accell siRNA reagents are guaranteed to silence target gene expression by at least 75% at the mRNA level when used under optimized conditions!
Synthetic sgRNAs for CRISPR-Cas9 gene editing
Synthetic single guide RNAs are easy to design and order through the CRISPR Design Tool!
Ideal for development of therapeutic gene editing applications.
Create a custom library of pre-designed reagents for RNAi, CRISPR, or Over-expression
When Dharmacon pre-defined libraries do not match your experimental requirements, you can make your own custom library with ease, speed and economy.
Online design & ordering tools for precise CRISPR-mediated genome editing
Design custom ssDNA donor oligos.
Generate donor plasmids to insert mKate2, EGFP, or a custom sequence.
CRISPR-Cas9 Gene Editing - Guaranteed!
Accelerate your path to high-confidence gene knockdown results with the Edit-R CRISPR-Cas9 platform. All Edit-R predesigned DNA and synthetic RNA reagents are GUARANTEED to cleave their genomic target site! Whether you are working with a few genes or the whole human genome, your choice for high-quality guide RNA is clear.
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This webinar shows several applications of the CRISPR-Cas9 system specifically for creation of a knockout cell lines, precise HDR mediated knock-in, and CRISPR activation of gene transcription.
Get the facts about CRISPR-Cas9 synthetic sgRNA and crRNA, how do they really compare?
The University of Colorado’s RNA Club empowers advancements in RNA-based applications and research areas.
Learn how to use the CRISPR Design Tool to design guide RNAs and how to easily order 20 or more synthetic gRNAs in a multiwell plate.